Ka-hortagga aadanaha GDF15 Antibody, Mouse Monoclonal

Warbixin guud
Qodobka kobaca-kala duwanaanta 15 (GDF15), oo sidoo kale loo yaqaan MIC-1, waa xubin qarsoodi ah oo ka mid ah factor koritaanka isbeddelka (TGF) -β superfamily, oo ah cunsur cusub oo ka hortagga hypertrophic ee wadnaha.GDF-15 / GDF15 laguma muujiyo wadnaha caadiga ah ee qaangaarka laakiin waxaa loo soo jiiday iyada oo laga jawaabayo xaaladaha kor u qaadaya hypertrophy iyo wadna xanuunka oo fidsan waxaana si weyn loogu muujiyaa beerka.GDF-15 / GDF15 waxay door ku leedahay nidaaminta dariiqyada caabuqa iyo apoptotic ee unugyada dhaawacan iyo inta lagu jiro hababka cudurka.GDF-15/GDF15 waxa loo farsameeyay sidii unugyo horudhac ah oo lagu farsameeyo goobta jeexjeexan si loo sii daayo xayndaabyada C-terminal oo ay ku jiraan ujeedo sifo ah oo ah 7 cysteines la ilaaliyo ee borotiinka qaangaarka ah.GDF-15/GDF15 muujinta xad dhaafka ah ee ka dhalatay qaybta erythroid-ka ee la ballaariyay waxay gacan ka geysataa culeyska birta ee thalassaemia syndromes iyadoo la joojinayo muujinta hepcidin.