Ka-hortagga aadanaha Her2 Antibody, Mouse Monoclonal
Faahfaahinta alaabta
Warbixin guud
Reseptor factor factor koritaanka epidermal 2 (HER2), oo sidoo kale loo yaqaan ErbB2, NEU, iyo CD340, waa nooc I xuub glycoprotein oo iska leh factor koritaanka epidermal (EGF) qoyska reseptor.borotiinka HER2 ma xidhi karo arrimaha koritaanka sababta oo ah la'aanta domain xidhitaankeeda oo iskeed ah oo si iskeed ah loo xakameeyey.Si kastaba ha noqotee, HER2 waxay samaysaa heterodimer oo leh xubnaha kale ee ligand-ku xidhan ee EGF reseptor, sidaa darteed waxay dejinaysaa isku xidhka ligand waxayna kor u qaadaysaa firfircoonida dhexdhexaadinta kinase ee molecules-ka hoose.HER2 waxay door muhiim ah ka ciyaartaa horumarka, fidinta unugyada iyo kala duwanaanta.Hidde-sidayaasha HER2 ayaa lagu soo warramey in ay la xiriirto malignant iyo saadaal liidata ee kansarrada badan, oo ay ku jiraan naasaha, prostate, ugxan-sidaha, kansarka sanbabada iyo wixii la mid ah.
Guryaha
| Lammaanaha Talada | CLIA (La-qabsashada): 14-2~ 15-6 15-6~ 2-10 |
| daahirnimo | >95%, waxaa go'aamiyay SDS-PAGE |
| Habaynta kaydka | PBS, pH7.4. |
| Kaydinta | Ku kaydi xaaladaha nadiifka ah -20 ℃ ilaa -80 ℃ markaad hesho. Waxaan ku talinaynaa in loo qaybiyo borotiinka tiro yar si loo kaydiyo ugu fiican. |
Macluumaadka Dalabka
| Magaca Alaabta | BisadMaya | Aqoonsiga Clone |
| Her2 | AB0078-1 | 14-2 |
| AB0078-2 | 15-6 | |
| AB0078-3 | 2-10 |
Fiiro gaar ah: Bioantibody waxa lagu beddeli karaa tiro marka loo eego baahidaada.
Xigasho
1.Krawczyk N, iyo al.(2009) Xaaladda HER2 ee unugyada burooyinka la faafiyay ee joogtada ah ka dib daawaynta adjuvant waxay ka duwanaan kartaa heerka HER2 ee bilowga ah ee burada aasaasiga ah.Ka-hortagga kansarka Res.29 (10): 4019-24.
