Ka-hortagga bini'aadamka CHI3L1 Antibody, monoclonal aadanaha

Warbixin guud
Chitinase-3-sida borotiinka 1 (CHI3L1) waa heparin-ku-xidha glycoprotein sir ah kaas oo muujintiisa ay la xiriirto guuritaanka unugyada muruqa siman ee xididdada dhiigga.CHI3L1 waxaa lagu muujiyay heerar sare dhaqamada VSMC ee nodular postconfluent iyo heerar hoose ee dhaqamada fidinta qulqulka hoose.CHI3L1 waa unug xaddidan, lectin chitin-ku-xidhan iyo xubin ka tirsan qoyska glycosyl hydrolase 18. Si ka duwan kuwa kale oo badan oo monocyto / macrophage calamadaha, muujintiisa ayaa ka maqan monocytes iyo xoog leh oo soo jiidatay inta lagu jiro marxaladaha dambe ee kala duwanaanshaha macrophage aadanaha.Heerarka sare ee CHI3L1 waxay la xiriiraan xanuunada muujinaya kororka wareegga unugyada isku xiran, sida rheum atoid, arthritis, osteoarthritis, scleroderma, iyo cirrhosis ee beerka, laakiin waxaa lagu soo saaraa carjawda deeq-bixiyeyaashii hore ama bukaanada qaba osteoarthritis.CHI3L1 si aan caadi ahayn ayaa loogu muujiyay hippocampus maaddooyinka qaba shisoofrani waxaana laga yaabaa inay ku lug yeelato jawaabta gacanta ee dhacdooyinka deegaanka ee kala duwan ee la soo sheegay inay kordhinayaan halista shisoofrani.