Ka-hortagga aadanaha IGFBP-1 Antibody, Mouse Monoclonal
Faahfaahinta alaabta
Warbixin guud
IGFBP1, oo sidoo kale loo yaqaan IGFBP-1 iyo insuliin-sida korriinka borotiinka-ku xidhanaya borotiinka 1, waa xubin ka mid ah qoyska borotiinka kobaca insulin-sida.IGF xidhitaanka borotiinada (IGFBPs) waa borotiinada 24 ilaa 45 kDa.Dhammaan lixda IGFBPs waxay wadaagaan 50% homology waxayna leeyihiin xiriiro isku xiran oo loogu talagalay IGF-I iyo IGF-II oo isku mid ah cabbirka isku midka ah ee ligands ee IGF-IR.Borotiinnada IGF-ku-xidha waxay sii dheereeyaan nolosha nuska ah ee IGF-yada waxaana lagu muujiyey inay joojiyaan ama kicinayaan saamaynta kor-u-qaadista IGF-yada ee dhaqanka unugyada.Waxay beddelaan is-dhexgalka IGF-yada iyo soo-dhoweyaasha dusha unugga.IGFBP1 waxay leedahay IGFBP domain iyo tayrooglobulin-nooca I.Waxay isku xidhaa labada arrimood ee koritaanka insulin-sida (IGFs) I iyo II waxayna ku wareegaysaa balaasmaha.Isku-xidhka borotiinkani wuxuu dheereeyaa nolosha nuska ah ee IGF-yada waxayna beddelaan isdhexgalka ay la leeyihiin soo-dhoweynta dusha unugyada.
Guryaha
| Lammaanaha Talada | CLIA (La-qabsashada): 4H6-2 ~ 4C2-3 4H6-2 ~ 2H11-1 |
| daahirnimo | >95% sida ay go'aamisay SDS-PAGE. |
| Habaynta kaydka | 20mM PB, 150mM NaCl, 0.1% Proclin 300, pH7.4 |
| Kaydinta | Ku kaydi xaaladaha nadiifka ah -20 ℃ ilaa -80 ℃ markaad hesho. Waxaan ku talinaynaa in loo qaybiyo borotiinka tiro yar si loo kaydiyo ugu fiican. |
Isbarbardhigga Tartanka
| Bioantibody | Kiis Caafimaad ahaan La Ogaaday | Wadarta | |
| Wanagsan | xun | ||
| Wanagsan | 35 | 0 | 35 |
| xun | 1 | 87 | 88 |
| Wadarta | 36 | 87 | 123 |
| Gaar ahaan | 100% | ||
| Dareenka | 97% | ||
Macluumaadka Dalabka
| Magaca Alaabta | BisadMaya | Aqoonsiga Clone |
| IGFBP-1 | AB0028-1 | 4H6-2 |
| AB0028-2 | 4C2-3 | |
| AB0028-3 | 2H11-1 | |
| AB0028-4 | 3G12-11 |
Fiiro gaar ah: Bioantibody waxa lagu beddeli karaa tiro marka loo eego baahidaada.
Xigasho
1.Rutanen EM .1: US 1996.
2.Harman, S, Mitchell, iyo al.Heerarka Serum ee Insulin-Sida Kobaca Factor I (IGF-I), IGF-II, IGF-Binding Protein-3, iyo Prostate-Specific Antigen sida saadaaliyayaasha Kansarka qanjirka 'prostate' [J].Journal of Clinical Endocrinology & Metabolism, 2000.
