Ka-hortagga aadanaha ee MMP-3 Antibody, Mouse Monoclonal

Warbixin guud
Matrix metallopeptidase 3 (oo loo soo gaabiyo MMP3) ayaa sidoo kale loo yaqaan stromelysin 1 iyo progelatinase.MMP3 waa xubin ka mid ah qoyska matrix metalloproteinase (MMP) kuwaas oo xubnahooda ay ku lug leeyihiin burburinta matrixka ka baxsan hababka jireed ee caadiga ah, sida korriinka uurjiifka, taranka, dib u habeynta unugyada, iyo hababka cudurada oo ay ku jiraan arthritis iyo metastasis.Sida endopeptidase-ku-tiirsanaanta zinc-ku-tiirsanaanta, MMP3 waxay ku shaqeysaa shaqadeeda inta badan matrix-ka-ka-baxsan.Borootiinkan waxa ka shaqaysiiya laba horjooge oo waaweyn oo endogenous: alfa2-macroglobulin iyo nudaha inhibitors of metalloproteases (TIMPs).MMP3 waxay door dhexe ka ciyaartaa hoos u dhigida noocyada kolajka II, III, IV, IX, iyo X, proteoglycans, fibronectin, laminin, iyo elastin.Sidoo kale, MMP3 waxay firfircooni kartaa MMP-yada kale sida MMP1, MMP7, iyo MMP9, taasoo ka dhigaysa MMP3 muhiim u ah dib-u-qaabaynta unugyada isku xidhan.Habacsanaanta MMP-yada ayaa lagu lug yeeshay cudurro badan oo ay ku jiraan arthritis-ka, boogaha daba-dheeraada, encephalomyelitis, iyo kansarka.Kahortagayaasha synthetic ama dabiiciga ah ee MMP-yada waxay keenaan xannibaadda metastasis-ka, halka kor-u-qaadista MMP-yada ay horseeday soo-galitaanka unugyada kansarka.